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Last updated: May 15, 2018

Publications and submitting to public repositories

Funding bodies such as the National Health and Medical Research Council (NHMRC) encourage researchers to disseminate and share their research data through publicly accessible databases or repositories. The NHMRC does acknowledge that in practice, this would depend on several factors such as:

  • Sample source
  • Participant consent
  • Researchers’ state requirements
  • If the data is identifiable, re-identifiable or non-identifiable
  • If research was conducted as part of a consortium
Public repositories

Researchers and research laboratories can deposit clinically relevant variants in public archives such as ClinVar, which accepts both germline and somatic data and can hold submitted information until it is published. In cancer studies, community driven web resources include the Clinical Interpretations of Variants in Cancer (CIViC). Additional repositories such as GenBank accepts nucleic acid sequence data, and the Database of Short Genetic Variations (dbSNP), Genomic Structural Variations (dbVar) and Genotypes and Phenotypes (dbGaP) can accept research data of varying types.

Consensus is currently under development regarding common repositories where human genomic data or findings may be placed. Best practices for sharing genomic data and variants are also currently under development internationally.

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Publications

Most peer-reviewed publications require that data is shared or made available as it enables further research and replication of findings. Peer-reviewed publication usually requires that data is made available to editors and reviewers and often prefer that large data sets, mRNA and genomic sequences are shared via public repositories with appropriate access controls. However, special considerations regarding restrictions on access to sensitive, human data can be provided along with details of conditions upon which the data can be accessed or reused. 

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To seek advice on where might be appropriate to deposit and share your genomic findings, talk with your host organisation or institute.

For more information see - Making yourself data capable